James B. Bingham, PhD
James B. Bingham, PhD,
Chief Technology Officer
Dr. Bingham has a broad range of experience in the biopharmaceutical industry, including the fields of immunology, process development; process validation; formulation & stability; protein conjugation (ADC, Radionuclide and T1/2 extension); fill & finish; analytical method development, qualification, and validation; drug delivery technology; quality control; quality assurance; manufacturing; CMC regulatory affairs; and facilities engineering, design and construction. Dr. Bingham has served as the Chief Technology Officer for Clasp Therapeutics since March 2021. He was a founder of NextCure, Inc. in 2015 and served as the Chief Development Officer until March 2021. At NextCure he built the teams to support drug development, including all CMC functions, which included building the 2000L-scale GMP production facility, quality systems, QA and QC, CMC regulatory, controlled IT systems, and all supporting functions. Dr. Bingham was the SVP, Development, Manufacturing and Quality while part of the team building Amplimmune, Inc., and supported the sale and integration of Amplimmune to AstraZeneca. He also brings his experience as Associate Director of Microbial R&D with Lonza (and Cambrex) in financial management, organizational and resource management, corporate integration, customer relations and technical support of sales and marketing. Prior to joining Lonza, Dr. Bingham managed teams in process development, formulation, analytical, drug delivery and in-process technologies groups with Human Genome Sciences in Rockville, Maryland. Prior to his tenure at HGS, Jim was also employed at MedImmune in Gaithersburg, Maryland, (now part of Astra Zeneca) and Integrated Genetics in Framingham, Massachusetts (now part of Genzyme Corporation). Dr. Bingham received his Ph.D. in Biological Chemistry (protein chemistry) from The Johns Hopkins University and completed a concurrent fellowship at The Marine Biological Labs, Woods Hole, Massachusetts. His B.S. in Biology with a strong focus in organic chemistry and protein chemistry was earned at St. Michael’s College in Winooski, Vermont.